Adverse Events 3 Review required
PSUR Due 14d Pending draft
Literature Scan Last run today
Open Complaints 7 2 escalated
MDR Compliance EU On track

Post-Market Surveillance for Medical Devices

Your PMS process is a spreadsheet.
So is your next audit finding.

AxiraPMS automates complaint intake, adverse event classification, literature monitoring, and regulatory report generation — so your team stops chasing data and starts acting on it.

No pricing commitment. We're building this for QA/RA teams at SME device manufacturers — early access is free.

✓ You're on the list. We'll be in touch — and we may reach out to learn more about your current PMS process.

The problem

Risk

Missed MDR deadlines

Serious incidents must be reported within 15 days (EU MDR) or 30 days (FDA). Manual tracking in shared folders means things slip — and inspectors find them.

Efficiency

Literature search by hand

Your team manually checks PubMed, MAUDE, and EUDAMED on a quarterly cycle. New signals are already weeks old by the time they reach your PMS report.

Resource

PSUR writing takes days

Assembling a Periodic Safety Update Report from scattered complaint logs, trend data, and literature means someone's weekend disappearing before every renewal.

Compliance

Three regimes, one team

FDA, EU MDR, and MHRA have different timelines, templates, and terminology. Tracking multi-region obligations in a single spreadsheet is how things fall through the cracks.

"We have two people covering quality for three device lines across the EU and US. Half their time is finding information that should just be in front of them."

— Head of Quality, SME orthopaedic device manufacturer (paraphrased from discovery interviews)

01

Connect your complaint channels

Complaints come in via email, web form, or your existing CRM. AxiraPMS ingests them, auto-classifies severity, and flags anything that may require regulatory notification — in real time, not at the end of the quarter.

21 CFR Part 803 EU MDR Annex III MHRA
02

Automated literature & database monitoring

Define your device type and indication once. AxiraPMS runs scheduled scans of PubMed, FDA MAUDE, and EU EUDAMED, surfacing new signals directly to your dashboard — with suggested relevance scores so your team reviews what matters.

ISO 13485 §8.2.1 EU MDR Art. 83
03

Trend detection & signal analysis

Statistical trend analysis runs continuously across your complaint and adverse event data. When complaint rates deviate from baseline — or a new cluster emerges — you know before it becomes a pattern your notified body notices first.

21 CFR Part 822 EU MDR Art. 84
04

One-click PSUR & PMS report generation

When your reporting period closes, AxiraPMS compiles your complaint data, literature findings, trend analysis, and CAPA status into a structured report — formatted for EU MDR Annex III or FDA submission. Draft in minutes, not days.

EU MDR Annex III FDA QMSR 2026 ISO 13485
05

Audit-ready trail, always

Every review, classification, escalation, and report is timestamped and locked in an immutable log. When your notified body or the FDA comes for an inspection, your evidence file is already built.

ISO 13485 §4.2.5 21 CFR Part 820

Regulatory coverage

🇺🇸

United States — FDA

Post-market obligations under the updated QMSR (effective Feb 2026) and 21 CFR Parts 803, 806, and 822.

  • MDR-reportable event flagging
  • 21 CFR Part 822 plan alignment
  • CAPA workflow integration
  • FDA submission-ready exports
🇪🇺

European Union — MDR / IVDR

Full lifecycle support under EU MDR 2017/745 and IVDR 2017/746, including vigilance reporting obligations.

  • PSUR generation (Annex III)
  • EUDAMED signal monitoring
  • Vigilance timeline tracking
  • PMCF alignment
🇬🇧

United Kingdom — MHRA

Post-market surveillance under the UK MDR framework effective June 2025, aligned with MHRA's updated reporting structure.

  • MHRA adverse event reporting
  • UK-specific PMS report format
  • Divergence tracking from EU MDR
  • Device register integration
AxiraPMS Enterprise QMS
(Veeva, Sparta, TrackWise)
Spreadsheets & Manual
Setup time Days 3–12 months Immediate (but fragile)
Built for SMEs ✓ Core focus ✗ Priced for enterprise Sort of
Multi-region (FDA + EU + UK) ✓ Day one Add-on / configurable ✗ Manual tracking
Automated literature scan ✓ Included Limited / manual ✗ Fully manual
PSUR generation ✓ One click Template only ✗ 2–4 days of work
Pricing Transparent, per device line $50k–$200k+ / year Free but costly in time
Audit trail ✓ Automatic ✓ Yes ✗ Manual, unreliable

Be first when we launch.

We're reaching out to QA and RA teams at SME device companies before we write a single line of code. If PMS is painful for your team, we want to hear about it.

We'll also send a free PMS compliance checklist covering FDA, EU MDR, and MHRA obligations.

✓ You're on the list. Expect the compliance checklist in your inbox shortly.